Despite being vassals of the Hutts, some Klatooinians served the Galactic Republic as part of the Jedi Order. Three Klatooinian Jedi, Tarados Gon, Sta-Den Eekin, and Galdos Stouff were killed at the Battle of Geonosis.
Other Klatooinians served non-Hutt masters. In 30 BBY, dark side adept Profex Rynalla traveled to the planet Leritor with an entourage of two dozen Klatooinians, who served her as soldiers and slavers by kidnapping locals and forcing them to search for a secret Sith treasure.
During the Galactic Civil War, many young Klatooinians were inspired by the Rebel Alliance's message of freedom, and such Rebel victories as the Battle of Yavin. Many young Klatooinians turned their backs on tradition and rebelled against their former masters, sometimes joining up with smugglers, pirates, or rival criminal organizations. Some remained on their homeworld, hiding in the wilderness. A few, such as the technologist Rolanda Gron, managed to join the Rebellion themselves. During the Yuuzhan Vong War, a Klatooinian was a Galactic Alliance spy in the Peace Brigade.
Most Klatooinians, however, remained servants of the Hutts, working for the Klatooinian Trade Guild or various Hutt kajidics. Indeed, their servitude continued well into the time of the New Republic. Jabba the Hutt had several Klatooinians in his employ, including Barada, the chief mechanic on the Khetanna, and Umpass-stay, his bodyguard, spy, and drummer.